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Over the counter substitute for pantoprazole 40 mg /day. The combination of these approaches produces effective treatment of men with recurrent GD. The authors recommend that clinicians prescribe the combination of these approaches in addition to the primary treatment for patients with GD, and that this combination be used as a primary therapy prior to the initiation of hormone therapy. Clinicians should be aware, for the treatment of patients in whom risk factors for GD have been identified (Table1), that they may benefit from screening for such risk factors before initiating the treatment of interest. Table 1: Risk factors *These factors are also risk for breast cancer (see Box 1 in the 2). The following risk factors are associated with a significantly increased risk for developing GD: Prospective pregnancy (>1 year) History of hysterectomy Chronic hypertension Age > 40 years Caucasian ethnicity History of benign prostatic hypertrophy Pre-diagnosis hypertension BMI > 35 kg/m2 History of endometriosis Abnormal vaginal bleeding or at menopause The authors thank Dr. Kati Johnson and Richard Wiles for their comments on an earlier version of this manuscript. LITERATURE CITED 1. Norell P Clinical management of symptomatic penile cancer: the role of urodynamic therapy and systemic adjuvant chemotherapy. Clin Urol 1992; 10 : 508 – 13. 2. Lutwak AM Wiles RM Tumour biology of erectile dysfunction in men with disease of the prostate. J Steroid Biochem Mol Biol 2003; 88 : 935 – 51. 3. Koo CKJ Risacher SL Prostate cancer in men: implications for clinical care and research. J Clin Oncol 2007; 26 : 4983 – 99. 4. van de Weijden RN Boekhoorn MP Cone PJ Meyers RG van de Schutte JG Groom MW van den Eede WJ Huybrechts MJ Het GBM et al. The clinical prognosis of men with prostate cancer. BJ Urol 2007; 104 : 1117 – 24. 5. McKeown NM Schapire JF Jr Haney M Dolan RJ Moshun MJ O'Dell LJ Hinkin JV Lipsett M et al. The impact of advanced-stage prostate cancer on men's quality of life. J Clin Urol 2006; 53 : 831 – 6. Wiles RM Prostate cancer symptoms: from symptoms to disease : a guide the clinician. Br J Urol 2005; 92 : 3 – 5. 7. Wiles RM A practical guide to the diagnosis, management and outcome after breast cancer diagnosis and radiation therapy. 1st ed. Baltimore, MD : Williams and Wilkins; 1998. 8. Johnson TK Prostate cancer and genital in men: review of epidemiologic and experimental studies. Urology 1990; 40 : pantoprazole generic price 508 – 17. 9. Eriksson I Sorensen N Gustafsson T Ljunghannsson H Lindberg G Larsen L Torgersen K pantoprazole sod dr over the counter Thorsteinsson J Kjeli E et al. Hormonal treatment of prostate cancer in men. Curr Opin Endocrinol Diabetes 2004; 15 : 571 – 8. 10. pantoprazole cost australia Koo CKJ Deenen RK Fagerström L Torgersen KP Johnson TK Vlachopoulos JT Kuiper AJ Steffensen Sex differences in prostate cancer survival: Atorvastatin mylan 20 mg cena a meta-analysis. JAMA 2001; 285 : 2197 – 203. 11. Wiles RM Torgersen KP Johnson TK Deenen RK Binns P Sjogren O Lindberg G Risacher SL Moshun MJ et al. Sex differences in prostate cancer mortality after diagnosis and treatment: a meta-analysis. JAMA 2004; 292 : 2107 – 25. 12. Lindahl S Jørgensen T Eriksson I Torgersen KP Kjeli E K Thorvaldsen I Lind L Binns P Torgersen JT et al. Sexual minority men in the Scandinavian Prostate Cancer Study: survival in one decade. Eur Urol 2006; 51 : 1501 – 5. 13. Sjogren O Torgersen K Fagerström L Lindahl S Ljunghannsson H Binns P Jørgensen T Torgersen K KP Sjogren O et al. Sexual identity does not influence survival in prostate cancer patients: results from the Scandinavian Prostate Cancer Study. Eur Urol 2005; 50 : 1107 – 14. Deenen RK Gillett DA Kjeli E Johnson TK Torgersen KP.

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